Role of dietary polyphenols in the platelet aggregation network - a review of the in vitro studies
"Several epidemiological studies have reported a negative association between the intake of dietary polyphenols and the risk for cardiovascular disease (CVD). Conversely, a certain number of studies have reported no association."
"The activity of dietary polyphenols on CVD has been attributed to both their antioxidant activity in preventing LDL oxidation, and to their effect on the pathogenesis of thrombosis by interfering with platelet activation and function. In fact, platelets play an important role not only in the formation of actute thrombus and vessel occulsion, but also in the development of athersclerosis and CVD."
“The anti-aggregating effect depends in part on the specific structure of the phenol, even though great differences in anti-aggregating activity have been observed within each class.”
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