Citrus flavanoids and human cancers
"Nowadays cancers pose a great threat to the health of human beings. Based on studies on the flavonoids and other bioactive compounds of citrus fruits in current literature, it was widely suggested that the consumption of citrus fruits is beneficial to the prevention and treatment of human chronic diseases including cancers. In the past decades, the study concerning citrus flavonoids has covered various areas including the type, content and distribution of flavonoids in fruits; their variation between wild and cultivated genotypes; their antioxidant, anti-inflammation, anti-aging, antimicrobial and anticarcinogenic activities."
"Nuclear factor kappa B (NF-κB) transcription factors regulate several important physiologic processes of the cell, e.g., cell growth, and apoptosis. Thus, inhibition of NF-κB activation offers a potential strategy for treatment of different malignancies."