Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis
"Although urinary11-dehydro-TXB2 levels are largely suppressed with low-dose aspirin, incomplete suppression by aspirin predicts the future risk of vascular events and death in high-risk patients and may identify individuals who might benefit from treatments that more effectively block in vivo TX production or activity. Several disease-modifying agents, including lifestyle intervention, antidiabetic drugs and antiplatelet agents besides aspirin have been shown to reduce TX biosynthesis."
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