"Urinary 11-dh-TxB2 is a marker of whole-body inflammation and TxA2 biosynthesis contributed by platelet, leukocytes, and endothelial cells ."
"Among COVID-19 patients in our study, we found significantly elevated levels of u11-dh-TxB2 in patients with events compared with patients without events, and higher u11-dh-TxB2 levels were associated with prolonged hospitalization, death, and mechanical ventilation requirement. These observations highlight the potential prognostic utility of u11-dh-TxB2 in patients with COVID-19. This is in line with the observations of systemic cytokine storm, endothelial dysfunction, and elevated thrombotic risk in COVID-19."Read More